06 April 2011

No one in this world wants affected by lung cancer. However, although we suffered from lung cancer, does not mean a death sentence immediately fell in and we should give up waiting for death. Most importantly, we must know in advance what is lung cancer.

Lung cancer is a tumor that grows in the lungs. The most caused of the cells in the lung itself, but could be caused by cancer in other body parts that spread to the lungs. Although the main cause of 90% of lung cancer in men and 70% in women are smoking, but can also be caused by pollution or food.
Once we know that chemotherapy as a treatment for lung cancer, the patient is given an injection containing anti-cancer drugs which contain active ingredients such as taxane, cisplatin or carboplatin and others. This medicine works by killing cancer cells.

However, chemotherapy also has the effect of toxins that quite a lot. Generally, patients experience side effects such as nausea and vomiting and hair loss. Conditions like this will further reduce the quality of life of patients. Unfortunately, not only the death of cancer cells but healthy cells were also affected.

Along with advances in the medical world, the lung cancer patients have other treatment options, in addition to chemotherapy or surgery. Treatment is known as Targeted Therapy. Now begin to use drugs that have a specific target on the cell components that play a role in the process of cancer cell growth and division.

This new drug active ingredient is gefitinib. Currently, gefitinib has been the best option in many countries for the treatment of lung cancer. Drugs that have trademark-Iressa TM, is a pharmaceutical company Astra Zeneca production. The use of these drugs will inhibit the growth of tumor cells and inhibit blood vessel growth in cancer cells, thereby preventing the spread of tumor cells as well as enhances cancer cell death.


Targeted therapy has been shown to have benefit in cases of advanced cancer (3B). In the IDEAL study (Iressa Dose Evaluation in Advanced Lung Cancer) 1 and 2 be giving doses of 250 and 500 grams per day. The result is encouraging, that there is radiological and clinical improvement so as to provide increased life expectancy ranged from 7 to 7.6 months.

According to the results of clinical studies ISEL (Iressa Survival Evaluation in Lung Cancer) showed a very significant increase, especially in lung cancer patients of Asian ethnicity. Improving quality of life of patients by 40 percent compared with placebo use only less than 20 percent.

Iressa drug-shaped 250 mg tablets are given to patients with advanced lung cancer or stage IIIB and IV. This drug has toxic effects are relatively mild compared with conventional chemotherapy and reduce side effects, such as itching, diarrhea, and nausea.

Side effects above usually arise when patients took the drug Iressa in the weeks the second and third. These effects on even indicate if the drug Iressa was actually already working in our body.


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