11 October 2008

Medication Treatment Benefits
One person to another person has different respond each other to weight-loss medications. That’s why some people get more weight loss than others. Usually, the most reducing your weight occurs within 6 months since start consuming the medication. Weight-loss medications lead to an average weight loss of about 10 pounds more than what you might lose with non-drug obesity treatments.

In short term taking this medications, many individual reduce numbers of Health risk , includes improves blood pressure, blood cholesterol, triglycerides (fats), and insulin resistance (the body’s inability to use blood sugar).

In long-term use of weight-loss medications may help individuals keep off the weight they have lost. But still, more studies are needed to determine the long-term effects of weight-loss medications on weight and health.

Medication Treatment Risks and Concerns
Until now, research has yet to determine the long-term health effects of weight-loss drugs. Orlistat, one of the popular weight loss drug has been studied and investigated for 4 years, this was the longest drug ever studied. Most other studies have lasted 6 to 12 months or less. In addition, research has not examined rare side effects (those occurring in less than 1 per 1,000 patients). And still, the optimal duration of treatment is unknown.
  1. Abuse or dependence. These risks are not common with nonamphetamine appetite-suppressant medications. Your doctors should be cautious when they prescribe these medications for patients with a history of alcohol or other drug abuse.
  2. Tolerance. Some patients and doctors may be concerned that this shows tolerance to the medications, the leveling off may mean that the medication is no longer effective. It’s not clear if weight gain with continuing treatment is due to drug tolerance.
  3. Behavioral changes. Weight-loss drugs are not a magic pills or a one-shot fix for this chronic disease. People should combined with a healthy eating plan and increased physical activity.
Medication Treatment Side Effects

Sibutramine
  • Increases in blood pressure and heart rate, small but may become great concern in some patients.
  • Headache
  • Dry mouth
  • Constipation
  • Insomnia.
  • People shouldn’t take sibutaramine if had poorly controlled high blood pressure, heart disease, irregular heartbeat, or history of stroke.
  • Blood pressure should be monitored during taking this medication.
Orlista
  • Cramping
  • Intestinal discomfort
  • Passing gas
  • Diarrhea
  • Leakage of oily stool.
  • Reduces the absorption of some vitamins. People should take a multivitamin at least 2 hours before or after taking orlistat.
Those side effects are generally mild and temporary, but may be worsened by eating high-fat foods.

Fenfluramine and Dexfenfluramine
Combination with phentermine (fen/phen) were linked to the development of :
  • Valvular heart disease
  • Primary pulmonary hypertension (PPH)
These two disease potential and fatal disorder that affects the blood vessels in the lungs. There have been only a few case reports of PPH in patients taking phentermine alone, but the possibility that phentermine use is associated with PPH cannot be ruled out.

Phentermine, Phendimetrazine, and Diethylpropion
  • Sleeplessness
  • Nervousness
  • Euphoria (feeling of well-being).
  • You shouldn’t take these drugs if you have heart disease, high blood pressure, an overactive thyroid gland, or glaucoma.

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